Which leukemia can be identified by a positive periodic acid-Schiff stain?

Which leukemia can be identified by a positive periodic acid-Schiff stain?

• A. Acute myelogenous leukemia
• B. Chronic lymphocytic leukemia
• C. Acute lymphocytic leukemia
• D. Acute myelomonocytic leukemia

Answer: (C)

Acute lymphocytic leukemia (ALL) can be identified by a positive periodic acid-Schiff (PAS) stain due to the presence of lymphoblasts that have abundant glycogen. The PAS stain highlights polysaccharides, including glycogen, which is especially prevalent in the cells associated with ALL. This staining property aids in the differentiation of leukemias since other types do not exhibit the same level of glycogen deposits. In the context of acute lymphocytic leukemia, the positive PAS staining serves as a valuable diagnostic tool, allowing medical technologists to confirm the presence of lymphoblastic cells. This is particularly important in confirming the diagnosis of ALL, as its recognition can guide treatment options. The staining pattern is a characteristic feature utilized in the laboratory to differentiate ALL from other types of leukemia, making it crucial for accurate diagnosis and subsequent management.

Acute lymphocytic leukemia (ALL) can be identified by a positive periodic acid-Schiff (PAS) stain due to the presence of lymphoblasts that have abundant glycogen. The PAS stain highlights polysaccharides, including glycogen, which is especially prevalent in the cells associated with ALL. This staining property aids in the differentiation of leukemias since other types do not exhibit the same level of glycogen deposits.

In the context of acute lymphocytic leukemia, the positive PAS staining serves as a valuable diagnostic tool, allowing medical technologists to confirm the presence of lymphoblastic cells. This is particularly important in confirming the diagnosis of ALL, as its recognition can guide treatment options. The staining pattern is a characteristic feature utilized in the laboratory to differentiate ALL from other types of leukemia, making it crucial for accurate diagnosis and subsequent management.