What type of anemia is characterized by low red blood cell production due to bone marrow failure?

What type of anemia is characterized by low red blood cell production due to bone marrow failure?

• A. Aplastic anemia
• B. Hemolytic anemia
• C. Macrocytic anemia
• D. Hypochromic microcytic anemia

Answer: (A)

Aplastic anemia is characterized by a reduction or complete failure of the bone marrow to produce adequate amounts of blood cells, including red blood cells. This results in a significant decrease in the number of circulating red blood cells, leading to anemia. In aplastic anemia, the bone marrow is typically damaged due to factors such as autoimmune diseases, exposure to chemicals, radiation, or certain medications, which results in the absence of hematopoietic (blood-forming) stem cells. Understanding this condition highlights that it is distinct from other types of anemia, wherein the underlying causes differ. Hemolytic anemia involves the premature destruction of red blood cells, macrocytic anemia is often due to vitamin B12 or folate deficiencies leading to larger-than-normal red blood cells, and hypochromic microcytic anemia is typically associated with iron deficiency or chronic disease, resulting in small, pale red blood cells. Thus, aplastic anemia's defining feature is the failure of the bone marrow to produce blood cells adequately, which is why it is the correct answer.

Aplastic anemia is characterized by a reduction or complete failure of the bone marrow to produce adequate amounts of blood cells, including red blood cells. This results in a significant decrease in the number of circulating red blood cells, leading to anemia. In aplastic anemia, the bone marrow is typically damaged due to factors such as autoimmune diseases, exposure to chemicals, radiation, or certain medications, which results in the absence of hematopoietic (blood-forming) stem cells.

Understanding this condition highlights that it is distinct from other types of anemia, wherein the underlying causes differ. Hemolytic anemia involves the premature destruction of red blood cells, macrocytic anemia is often due to vitamin B12 or folate deficiencies leading to larger-than-normal red blood cells, and hypochromic microcytic anemia is typically associated with iron deficiency or chronic disease, resulting in small, pale red blood cells. Thus, aplastic anemia's defining feature is the failure of the bone marrow to produce blood cells adequately, which is why it is the correct answer.